GUJARAT STATE BIOTECHNOLOGY MISSION

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BT Research

Cancer Research Projects

Cancer Projects supported from 2021 to 2024

Sr. No. PI Institute Project title Broad Area Amount Sanctioned (INR) Year of Sanction
1 Dr. Sonal Rajiv Bakshi Nirma University Combination of Chimeric IL-15 and recombinant IL-12 as Immunotherapy for Lung Cancer and Colon Cancer Lung Cancer/Colon cancer 5996856 2021-22
2 Dr. Amit Mandoli NIPER-A Characterization of Transcriptional Landscape and Its Functional Role in Gingivo- Buccal Oral Squamous Cell Carcinoma for Targeted Drug Discovery Oral cancer 7825024 2021-22
3 Dr. Heena Dave Nirma University Therapeutic Targeting of Androgen Receptor as a biomarker to improve the clinical outcomes of Triple-Negative Breast Cancer Breast Cancer 4414856 2021-22
4 Dr. Mahesh Chhabria L. M. College of Pharmacy Design, Synthesis and Pharmacological Evaluation of ULK‐1 Inhibitors: Discovery of a novel ULK‐1 Inhibitor targeting autophagy and its combinatorial potential as anti‐cancer therapeutic modality in breast cancer Breast Cancer 1013160 2022-23
5 Dr. Randhir Kumar Indrashil University Synthesis, characterization of mannose carbon nanoparticles as a potent immune‐therapeutics regimen for ovarian cancer and Zirconium phosphate nano biocomposite films to enhance the success rate of bone
implants in tissue engineering.
Ovarian cancer 6280712 2022-23
6 Dr. Amit Shard NIPER-A Targeting Sweet Spot in Oral Cancer: Development of Novel Quinazolinones for Electrophillic Modification of Tumor Pyruvate Kinase M2 Oral Cancer 4803856 2022-23
7 Dr. Hetal Roy MSU Elucidate the role of folate in epigenetic regulation and prevention of neuroblastoma during early embryonic development neuroblastoma 4301856 2022-23
8 Dr. Bhaskar Datta IIT-Gn Identification of RNA G‐quadruplex structure in long noncoding RNAs (lncRNAs) dysregulated in ovarian cancer Ovarian cancer 3289656 2022-23
9 Dr. Prakash Prabhakaran Pillai MSU Role of long non-coding RNAs found in glioblastoma-derived extracellular vesicles in microglial dysregulation: Possible implications for tumour immunosuppressive microenvironment and biomarker discovery Brain cancer 5431856 2022-23
10 Dr. Neeru Singh IAR Design and Validation of miR200c Agomir as a novel combinatorial therapeutic strategy along with Olaparib against drug resistant BRCA1 mutated ovarian carcinomas Ovarian cancer 4640856 2022-23
11 Dr. Reena Rajput IAR Evaluation of chemi-vaccine candidate and novel ionic liquid based adjuvancy for improved efficacy against breast cancer Breast Cancer 3756856 2022-23
12 Dr. Vivek Tanavde Ahmedabad University Development of a nano-liposomal formulation for targeting chemo-resistant oral cancer stem cells Oral cancer 3480572 2022-23
13 Dr. Harsh Sheth FRIGE Prevalence and association of microsatellite instabilityand Lynch syndrome Pan-Cancer and development of a personalized cancer risk prediction tool for Lynch syndrome carriers in India Hereditary cancer risk 8177062 2023-24
14 Dr. Trupti Trivedi GCRI Establishment and Validation of CustomTargeted Gene Panel for Diffuse Glioma Patients- A Next Generation Sequencing Approach Brain cancer 6626320 2023-24
15 Prof. Tejal Mehta Nirma University Fabrication of Anti-EGFR and Phytoconstituentloaded Mucoadhesive Electrospun Nanofiber matsfor improved locoregionaltherapy of oral cancer Oral cancer 5782608 2023-24
16 Dr. Heena Dave Nirma University Exploring the molecular and cellular pathways responsible for pre‐metastatic niche to organotropic metastasis in Triple Negative Breast Cancer: Uncovering the Role of microRNAs Breast Cancer 7083464 2023-24
17 Dr. Bhumika Patel Nirma University Hit to Lead Optimization of NCEs as Selective Poly (ADP‐ribose) Polymerase1 (PARP1) Inhibitors for the Treatment of Breast Cancer Breast Cancer 4075856 2023-24
18 Dr. Bhoomika Patel National Forensic Sciences
University
Clinical evaluation of effect of metronomic chemotherapy in cachexia associated with triple negative breast cancer Breast Cancer 7013856 2023-24
19 Dr. Sharad Gupta IIT‐GN Targeted Protein Degradation of TDP‐43: Target validation and development of therapeutics against Triple Negative Breast Cancer Breast Cancer 4328072 2023-24
20 Dr. Anupama Modi GTU An integrative multi‐omics approach to the identification of Oral cancer biomarker(s) Oral cancer 5431856 2023-24

Network Program on Cancer Research

Gujarat State Biotechnology Mission has initiated Research Support Scheme for providing financial support to Universities/ Colleges/ Institutions. GSBTM has recommended 3 projects under the “Networking Program on Cancer Research”. Currently, the projects are sanctioned to The Gujarat Cancer & Research Institute, Ahmedabad and Gujarat Biotechnology Research Centre under this program; and they work in the area of Oral Cancer (Male) and Breast & Ovarian cancer (Female). The program is coordinated by GSBTM.


Project Coordinator
Dr. Prabhudas Patel,

Professor & Head, Cancer Biology Department,
The Gujarat Cancer & Research Institute. Project Coordinator for this program.


Sr. No. Investigator Project Title Institute
1 Dr. Hemangini Vora,
Dr. Prabhudas Patel,
Dr. Nandita Ghosh,
Dr. Pina Trivedi
Development and Validation of Biomarkers and Drug Targets by molecular profiling of Triple Negative Breast Cancer The Gujarat Cancer & Research Institute
2 Dr. Prabhudas Patel,
Dr. Hemangini Vora,
Dr. Trupti Trivedi,
Dr. Jayendra Patel
Development and Validation of Biomarker Panel for Early Detection and Enhanced Management of Oral (Buccal Mucosa) Cancer The Gujarat Cancer & Research Institute
3 Dr. Prabhudas Patel,
Dr. Shashank Pandya,
Dr. Franky Jha,
Dr. Hemangini Vora,
Dr. Madhvi Joshi
Development and Validation of Amplicon panel for Hereditary Breast and Ovarian Cancer in Indian population The Gujarat Cancer & Research Institute,
Gujarat Biotechnology Research Centre (GBRC)

GBRC
Gujarat Biotechnology Research Centre
CGRI
Gujarat Cancer & Research Institute
Dr. Madhvi Joshi Dr. Prabhudas Patel
Dr. Poonam Bhargava Dr. Hemangini Vora
- Dr. Apurva Patel
- Dr. Dhaval Jetly
- Dr. Franky Shah
- Dr. Jayendra Patel
- Dr. Nandita Ghosh
- Dr. Pina Trivedi
- Dr. Rakesh Vyas
- Dr. Shahshank Pandya
- Dr. Trupti Trivedi

Page last updated on: 6/1/2025

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